Isdin Isdinceutics A.G.E Reverse Night Repair Cream is a facial night cream formulated with Melatonin, which stimulates your antioxidant defences to combat the aggressions suffered during the day. Melatonin helps to repair the skin, recovering the levels of the main antioxidant defences. Melatonin increases the production of endogenous antioxidant enzymes, which help to combat the free radicals produced by oxidative stress to which we are exposed throughout the day. With Carnosine, which slows down the rate of formation of advanced glycation end-products (A.G.E.), which can impair the functionality of the collagen and elastin, and with Helichrysum Italicum, which stimulates the release of calming molecules, increasing the sensation of well-being.