Contrad Swiss CR500 Cartilage Protecting Topical Gel For Osteoarthritis, Pack of 4 Monodose Vial + 8 Patches

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    AED640.00
    Overview
    |To attenuate physiological degeneration of cartilage in osteoarthritis |To slow down cartilage degeneration associated with osteoarthritis |A pain management product for optimum joint and soft tissue wellness |Delivers desired action deep tissue by simple topical administration of a sticky patch |To restore mobility and strength |Self-penetrating gel imbued with SIGMOLECS® Technology |Can be applied in several areas, as needed, on the patient |Single dose gel containing SH-Polypeptide-85 and SH-Polypeptide-93 |Skin friendly; facilitate permeation through cell membranes |Engineered by Dr JO Serrentino for Contrad Swiss
    • To attenuate physiological degeneration of cartilage in osteoarthritis
    • To slow down cartilage degeneration associated with osteoarthritis
    • A pain management product for optimum joint and soft tissue wellness
    • Delivers desired action deep tissue by simple topical administration of a sticky patch
    • To restore mobility and strength
    • Self-penetrating gel imbued with SIGMOLECS® Technology
    • Can be applied in several areas, as needed, on the patient
    • Single dose gel containing SH-Polypeptide-85 and SH-Polypeptide-93
    • Skin friendly; facilitate permeation through cell membranes
    • Engineered by Dr JO Serrentino for Contrad Swiss
    • Contrad Swiss CR500 Cartilage Protecting Topical Gel For Osteoarthritis is optimal for attenuating the physiological degeneration of cartilage typical of osteoarthritic processes. CR500 is a hydrogel containing peptides and hyaluronic acid with a soothing action that helps prevent and attenuate the physiological degeneration of cartilage in osteoarthritis, thereby protecting against and slowing the progression of joint damage. The 500 Line of monodoses contains SIGMOLECS® Technology in that it designs scaled molecules that can easily penetrate the skin and enter deep tissue. Sigmolecs® Technology is an advanced chemical profiling through structural assembling of key molecules, mostly proteins and peptides, that form actuated molecules by specifically: Improving their bio-activity in solution and in vivo; Increasing their transmembrane penetration; Creating precise specificity of action, particularly in intracellular signaling. SIGMOLECS® molecules induce signals to key amino acid to trigger specific physiological and metabolic activity. This is done by grafting bioactive peptides or amino acid (AA) sequences onto a source molecule, usually a natural source protein like Soy protein or Collagen peptides. Sigmolecs® molecules are really like microchips carrying the information to program desired relief into the patient. CR500TM contains SH-Polypeptide-85 which codes for FGF-9 (aka Glia-Activating Factor) and SH-Polypeptide-93 which codes for Cellular Communication Network Factor 2 (CCN2). FGF-9 is important for the homeostasis of articular cartilage and plays a role in the correct formation of the joint space and the inhibition of endochondral ossification. The role of FGF9 in joint development and homeostasis is well supported by the literature, especially its role in controlling chondrocyte development and regulating bone growth, both of which contribute largely to the smooth movement of articulations and thus pain-free movement. Disequilibrium within this system will lead to degraded cartilage and the formation of mineralized “bony" deposits within the articulation leading to pain. CCN2 is known for its stimulatory effect on the production of extracellular matrix components, indeed disruption of CCN2 leads to defects in collagen III and IV, laminin, and importantly, hyaluronic acid production. The latter of which is crucial in the viscoelasticity of the synovial fluid that lines and lubricates the joints.
    • Prevents and attenuates physiological degeneration of cartilage
    • Helps lessen the joint pain and stiffness of osteoarthritis
    • Improves joint mobility and helps prevent tightening of the tissues around the joint
    • Helps you move pain free
    • Helps you remain active without making your symptoms worse
    • Offers better control of pain, which may improve how you feel and function physically
    • Improves sense of overall well-being with the decrease in the intensity of pain
    • For chronic osteoarthritis, an in situ application of two to four patches of CR500 surrounding the joint in question can be applied 1-2 x week for 1 month, then twice a month for 2-4 months. Several joints can be done at the same time. There is no limit to the amount of monodoses that can be used in one session.
    • It is important to cover the gel with an adhesive patch which is provided within the pack. DO NOT USE IT AS A TOPICAL RUB.
    • General Tips: Make sure the gel does not contact the adhesive sides of the patch. The patch should remain in situ for a minimum of 2.5 hours and optimally for 6-8 hours. There is no limit, the patients can even remove the patch the next day. It is important to tell patients not to get the patch wet once in place. You can wipe the area with alcohol to ensure a clean dry surface. It is important to apply the patch to clean dry skin.
    • Follow the link to learn how to correctly apply the 500 Line monodoses in just 1 minute: https://www.contrad.ch/video/CONTRAD_line_500.mp4
    More Information
    Age Group18+ Years
    BrandContrad Swiss
    GenderUnisex
    Life StageAdult
    FormGel
    Pack SpecificationBox
    ApplicationBody
    UsageTopical
    Storage TemperatureCool Temperature
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